Lung Cancer Research Today is a free monthly online journal that collates and summarizes the latest research about Lung Cancer, including details on symptoms, smoking, genetics, treatment, causes.

Remote intrapulmonary spread of recurrent respiratory papillomatosis with malignant transformation.

Katz SL, Das P, Ngan BY, Manson D, Pappo AS, Sweezey NB, Solomon MP

Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.

Recurrent respiratory papillomatosis is the most common neoplasm of the larynx in childhood. Extension into lung parenchyma occurs in less than 1% of patients and has a low risk of malignant transformation. Treatment options for intrapulmonary spread have shown limited success. We describe a case of recurrent respiratory papillomatosis with extensive parenchymal involvement and adenosquamous carcinoma in a 14-year-old girl.

Published 5 January 2005 in Pediatr Pulmonol, 39(2): 185-8.
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