Lung Cancer Research Today is a free monthly online journal that collates and summarizes the latest research about Lung Cancer, including details on symptoms, smoking, genetics, treatment, causes. | ||||||||
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Surgical treatment of superior sulcus tumors.Koizumi K, Haraguchi S, Hirata T, Hirai K, Mikami I, Yamagishi S, Okada D, Kinoshita H, Enomoto Y, Nakajima Y, Shimizu K Department of Surgery II, Division of Thoracic Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan. PURPOSE: To access the clinical outcome of patients with superior sulcus tumor. METHODS: We reviewed the records of 16 patients who underwent surgery for a superior sulcus tumor between 1988 and 2003, focusing on the type of surgery. RESULTS: All 16 patients underwent en bloc lung and chest wall resection, which was done as pneumonectomy in 1 patient and lobectomy in 15. Complete resection was achieved in 11 patients, but incomplete resection was done in 5 patients because microscopic examination revealed positive surgical margins. Eight patients underwent partial vertebrectomy and 1 patient had combined resection of the subclavian artery. There was no postoperative mortality. All patients received pre- or postoperative adjuvant therapy, or both. The overall 5-year survival rate was 31.0%. The 5-year survival rate was higher after complete resection than after incomplete resection (59.3% vs 0%, P = 0.08). Patients who underwent complete resection for vertebral invasion and those who did not had 5-year survival rates of 66.7% and 0%, respectively (P = 0.17). Patients who underwent preoperative induction therapy followed by complete resection and those who did not had 5-year survival rates of 80% and 0%, respectively (P = 0.009). CONCLUSION: Although superior sulcus tumors are still complex, preoperative induction therapy followed by complete resection seemed effective for prolonging survival. Published 2 May 2005 in Surg Today, 35(5): 357-63.
© 2004-2008 Lung Cancer Research Today. All Rights Reserved. |
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