Lung Cancer Research Today is a free monthly online journal that collates and summarizes the latest research about Lung Cancer, including details on symptoms, smoking, genetics, treatment, causes.

Volume 2 (2005), Issue 6 (June)

1. ZD6474--clinical experience to date.
   Br J Cancer, 92: S14-20. [Abstract] [Full-text]
2. Increased lung metastasis in transgenic NM23-Null/SV40 mice with hepatocellular carcinoma.
   J Natl Cancer Inst, 97(11): 836-45. [Abstract] [Full-text]
3. DNA methylation disturbances as novel therapeutic target in lung cancer: preclinical and clinical results.
   Crit Rev Oncol Hematol, 55(1): 1-11. [Abstract] [Full-text]
4. Discovery of a novel small molecule, 1-ethoxy-3-(3,4-methylenedioxyphenyl)-2-propanol, that induces apoptosis in A549 human lung cancer cells.
   Bioorg Med Chem, 13(13): 4176-83. [Abstract] [Full-text]
5. Increased renal calcium reabsorption by parathyroid hormone-related protein is a causative factor in the development of humoral hypercalcemia of malignancy refractory to osteoclastic bone resorption inhibitors.
   Clin Cancer Res, 11(11): 4198-203. [Abstract] [Full-text]
6. Chemotherapy induces the expression of cyclooxygenase-2 in non-small cell lung cancer.
   Clin Cancer Res, 11(11): 4191-7. [Abstract] [Full-text]
7. Prediction of lymph node metastasis by analysis of gene expression profiles in primary lung adenocarcinomas.
   Clin Cancer Res, 11(11): 4128-35. [Abstract] [Full-text]
8. Prognostic implications of cell cycle, apoptosis, and angiogenesis biomarkers in non-small cell lung cancer: a review.
   Clin Cancer Res, 11(11): 3974-86. [Abstract] [Full-text]
9. Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels.
   Cancer Res, 65(11): 4739-46. [Abstract] [Full-text]
10. Requirement for focal adhesion kinase in the early phase of mammary adenocarcinoma lung metastasis formation.
    Cancer Res, 65(11): 4698-706. [Abstract] [Full-text]
11. Predictive value of image cytometry for diagnosis of lung cancer in heavy smokers.
    Eur Respir J, 25(6): 956-63. [Abstract] [Full-text]
12. A comparison of video and autofluorescence bronchoscopy in patients at high risk of lung cancer.
    Eur Respir J, 25(6): 951-5. [Abstract] [Full-text]
13. Estrogen or antiprogestin treatment induces complete regression of pulmonary and axillary metastases in an experimental model of breast cancer progression.
    Carcinogenesis, 26(6): 1055-63. [Abstract] [Full-text]
14. Functional haplotypes in the promoter of matrix metalloproteinase-2 and lung cancer susceptibility.
    Carcinogenesis, 26(6): 1117-21. [Abstract] [Full-text]
15. 22-Oxa-1alpha,25-dihydroxyvitamin D3 inhibits metastasis and angiogenesis in lung cancer.
    Carcinogenesis, 26(6): 1044-54. [Abstract] [Full-text]
16. Improving the quality of palliative care for ambulatory patients with lung cancer.
    BMJ, 330(7503): 1309-13. [Abstract] [Full-text]
17. Nodule detection in digital chest radiography: summary of the RADIUS chest trial.
    Radiat Prot Dosimetry, 114(1): 114-20. [Abstract] [Full-text]
18. Nodule detection in digital chest radiography: effect of anatomical noise.
    Radiat Prot Dosimetry, 114(1): 109-13. [Abstract] [Full-text]
19. Nodule detection in digital chest radiography: part of image background acting as pure noise.
    Radiat Prot Dosimetry, 114(1): 102-8. [Abstract] [Full-text]
20. Nodule detection in digital chest radiography: effect of system noise.
    Radiat Prot Dosimetry, 114(1): 97-101. [Abstract] [Full-text]
21. Nodule detection in digital chest radiography: effect of nodule location.
    Radiat Prot Dosimetry, 114(1): 92-6. [Abstract] [Full-text]
22. Nodule detection in digital chest radiography: introduction to the RADIUS chest trial.
    Radiat Prot Dosimetry, 114(1): 85-91. [Abstract] [Full-text]
23. Tumour cell frequency in pleural lavage in cases with stage I epidermoid lung cancer with no visceral pleural involvement.
    ANZ J Surg, 75(5): 300-1. [Abstract] [Full-text]
24. Four-dimensional multislice computed tomography for determination of respiratory lung tumor motion in conformal radiotherapy.
    Int J Radiat Oncol Biol Phys, 62(3): 888-92. [Abstract] [Full-text]
25. Combination of longitudinal and circumferential three-dimensional esophageal dose distribution predicts acute esophagitis in hypofractionated reirradiation of patients with non-small-cell lung cancer treated in stereotactic body frame.
    Int J Radiat Oncol Biol Phys, 62(3): 652-8. [Abstract] [Full-text]
26. "Anatomically-correct" dosimetric parameters may be better predictors for esophageal toxicity than are traditional CT-based metrics.
    Int J Radiat Oncol Biol Phys, 62(3): 645-51. [Abstract] [Full-text]
27. Pulmonary function changes after radiotherapy in non-small-cell lung cancer patients with long-term disease-free survival.
    Int J Radiat Oncol Biol Phys, 62(3): 639-44. [Abstract] [Full-text]
28. Challenges in defining radiation pneumonitis in patients with lung cancer.
    Int J Radiat Oncol Biol Phys, 62(3): 635-8. [Abstract] [Full-text]
29. Quantification of regional ventilation from treatment planning CT.
    Int J Radiat Oncol Biol Phys, 62(3): 630-4. [Abstract] [Full-text]
30. Dosimetric correlations of acute esophagitis in lung cancer patients treated with radiotherapy.
    Int J Radiat Oncol Biol Phys, 62(3): 626-9. [Abstract] [Full-text]
31. Computer-aided lung nodule detection in CT: results of large-scale observer test.
    Acad Radiol, 12(6): 681-6. [Abstract] [Full-text]
32. The suppressed proliferation and premature senescence by ganciclovir in p53-mutated human non-small-lung cancer cells acquiring herpes simplex virus-thymidine kinase cDNA.
    Cancer Detect Prev, 29(3): 286-93. [Abstract] [Full-text]
33. Mutational analysis of EGFR and K-RAS genes in lung adenocarcinomas.
    Virchows Arch, 446(5): 483-8. [Abstract] [Full-text]
34. HERG K+ channel expression-related chemosensitivity in cancer cells and its modulation by erythromycin.
    Cancer Chemother Pharmacol, 56(2): 212-20. [Abstract] [Full-text]
35. Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target of rapamycin signaling pathway and activation of hypoxia inducible factor-1alpha.
    J Biol Chem, 280(23): 22473-81. [Abstract] [Full-text]
36. In vivo antitumor efficacy of 17-DMAG (17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride), a water-soluble geldanamycin derivative.
    Cancer Chemother Pharmacol, 56(2): 115-25. [Abstract] [Full-text]
37. Serum carcinoembryonic antigen as a predictive marker for sensitivity to gefitinib in advanced non-small cell lung cancer.
    Eur J Cancer, 41(9): 1286-90. [Abstract] [Full-text]
38. Hui and Walter's latent-class reference-free approach may be more useful in assessing agreement than diagnostic performance.
    J Clin Epidemiol, 58(7): 688-700. [Abstract] [Full-text]
39. High-dose radiotherapy in trimodality treatment of Pancoast tumors results in high pathologic complete response rates and excellent long-term survival.
    J Thorac Cardiovasc Surg, 129(6): 1250-7. [Abstract] [Full-text]
40. Evaluation of cyclooxygenase-2 inhibition in an orthotopic murine model of lung cancer for dose-dependent effect.
    J Thorac Cardiovasc Surg, 129(6): 1242-9. [Abstract] [Full-text]
41. Objective radiologic analysis of ground-glass opacity aimed at curative limited resection for small peripheral non-small cell lung cancer.
    J Thorac Cardiovasc Surg, 129(6): 1226-31. [Abstract] [Full-text]
42. Examining population stratification via individual ancestry estimates versus self-reported race.
    Cancer Epidemiol Biomarkers Prev, 14(6): 1545-51. [Abstract] [Full-text]
43. Sex differences in risk of lung cancer associated with methylene-tetrahydrofolate reductase polymorphisms.
    Cancer Epidemiol Biomarkers Prev, 14(6): 1477-84. [Abstract] [Full-text]
44. A phase II study of docetaxel and infusional cisplatin in advanced non-small-cell lung cancer.
    Chemotherapy, 51(2): 120-5. [Abstract] [Full-text]
45. Frequency of SOX Group B (SOX1, 2, 3) and ZIC2 antibodies in Turkish patients with small cell lung carcinoma and their correlation with clinical parameters.
    Cancer, 103(12): 2575-83. [Abstract] [Full-text]
46. Distribution according to histologic type and outcome by gender and age group in Taiwanese patients with lung carcinoma.
    Cancer, 103(12): 2566-74. [Abstract] [Full-text]
47. Prognostic value of cyclin D1 overexpression in correlation with pRb and p53 status in non-small cell lung cancer (NSCLC).
    J Cancer Res Clin Oncol, 131(7): 479-85. [Abstract] [Full-text]
48. Early lung cancer detection using spiral computed tomography and positron emission tomography.
    Am J Respir Crit Care Med, 171(12): 1378-83. [Abstract] [Full-text]
49. Aberrant methylation and loss of expression of O-methylguanine-DNA methyltransferase in pulmonary squamous cell carcinoma and adenocarcinoma.
    Pathol Int, 55(6): 303-9. [Abstract] [Full-text]
50. A novel germline mutation, 1793delG, of the MEN1 gene underlying multiple endocrine neoplasia type 1.
    Jpn J Clin Oncol, 35(5): 280-2. [Abstract] [Full-text]
51. Changes in angiogenic growth factor levels after gefitinib treatment in non-small cell lung cancer.
    Jpn J Clin Oncol, 35(5): 233-8. [Abstract] [Full-text]
52. An accelerated radiotherapy scheme using a concomitant boost technique for the treatment of unresectable stage III non-small cell lung cancer.
    Jpn J Clin Oncol, 35(5): 239-44. [Abstract] [Full-text]
53. False-positive findings on [18F]FDG-PET caused by non-neoplastic cellular elements after neoadjuvant chemoradiotherapy for non-small cell lung cancer.
    Jpn J Clin Oncol, 35(5): 271-3. [Abstract] [Full-text]
54. Primary pulmonary synovial sarcoma confirmed by molecular detection of SYT-SSX1 fusion gene transcripts: a case report and review of the literature.
    Jpn J Clin Oncol, 35(5): 274-9. [Abstract] [Full-text]
55. Small cell carcinoma of the lung exclusively localized within the left descending pulmonary artery.
    Chest, 127(6): 2273-6. [Abstract] [Full-text]
56. Visceral pleural perforation in two cases of ultrathin bronchoscopy.
    Chest, 127(6): 2271-3. [Abstract] [Full-text]
57. CT-guided interstitial single-fraction brachytherapy of lung tumors: phase I results of a novel technique.
    Chest, 127(6): 2237-42. [Abstract] [Full-text]
58. Transbronchial needle aspirates: comparison of two preparation methods.
    Chest, 127(6): 2015-8. [Abstract] [Full-text]
59. A prospective feasibility study of bronchial thermoplasty in the human airway.
    Chest, 127(6): 1999-2006. [Abstract] [Full-text]
60. Smoking and timing of cessation: impact on pulmonary complications after thoracotomy.
    Chest, 127(6): 1977-83. [Abstract] [Full-text]
61. Pulmonary metastases after nephrectomy only for small, stage I/favorable-histology Wilms' tumor.
    Pediatr Surg Int, 21(6): 470-3. [Abstract] [Full-text]
62. Lung resection in patients with preoperative FEV1 < 35% predicted.
    Chest, 127(6): 1984-90. [Abstract] [Full-text]
63. Beta-carotene interaction with NNK in the AJ-mouse model: effects on cell proliferation, tumor formation and retinoic acid responsive genes.
    Biochim Biophys Acta, 1740(2): 179-88. [Abstract] [Full-text]
64. Five cardiac hormones decrease the number of human small-cell lung cancer cells.
    Eur J Clin Invest, 35(6): 388-98. [Abstract] [Full-text]
65. Survival trees for analyzing clinical outcome in lung adenocarcinomas based on gene expression profiles: identification of neogenin and diacylglycerol kinase alpha expression as critical factors.
    J Comput Biol, 12(5): 534-44. [Abstract] [Full-text]
66. Small-cell tumors of the liver: a cytological study of 91 cases and a review of the literature.
    Diagn Cytopathol, 33(1): 8-14. [Abstract] [Full-text]
67. Metastatic mammary carcinomas with endocrine features: potential diagnostic pitfalls.
    Diagn Cytopathol, 33(1): 49-53. [Abstract] [Full-text]
68. Methylation profiling of archived non-small cell lung cancer: a promising prognostic system.
    Clin Cancer Res, 11(12): 4400-5. [Abstract] [Full-text]
69. Gefitinib-sensitive mutations of the epidermal growth factor receptor tyrosine kinase domain in chinese patients with non-small cell lung cancer.
    Clin Cancer Res, 11(12): 4289-94. [Abstract] [Full-text]
70. Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer.
    Cancer Res, 65(12): 5211-20. [Abstract] [Full-text]
71. TP53 and KRAS mutation load and types in lung cancers in relation to tobacco smoke: distinct patterns in never, former, and current smokers.
    Cancer Res, 65(12): 5076-83. [Abstract] [Full-text]
72. Element array by scanning X-ray fluorescence microscopy after cis-diamminedichloro-platinum(II) treatment.
    Cancer Res, 65(12): 4998-5002. [Abstract] [Full-text]
73. [99mTcOAADT]-(CH2)2-NEt2: a potential small-molecule single-photon emission computed tomography probe for imaging metastatic melanoma.
    Cancer Res, 65(12): 4979-86. [Abstract] [Full-text]
74. Aerosol gemcitabine inhibits the growth of primary osteosarcoma and osteosarcoma lung metastases.
    Int J Cancer, 116(3): 458-63. [Abstract] [Full-text]
75. Case-control study of familial lung cancer risks in UK women.
    Int J Cancer, 116(3): 445-50. [Abstract] [Full-text]
76. Parathyroid hormone-related protein (PTHrP) as a causative factor of cancer-associated wasting: possible involvement of PTHrP in the repression of locomotor activity in rats bearing human tumor xenografts.
    Int J Cancer, 116(3): 471-8. [Abstract] [Full-text]
77. Physical activity and risk for lung cancer in a Danish cohort.
    Int J Cancer, 116(3): 439-44. [Abstract] [Full-text]
78. Cellular and pharmacogenetics foundation of synergistic interaction of pemetrexed and gemcitabine in human non-small-cell lung cancer cells.
    Mol Pharmacol, 68(1): 110-8. [Abstract] [Full-text]
79. Identification of bronchioalveolar stem cells in normal lung and lung cancer.
    Cell, 121(6): 823-35. [Abstract] [Full-text]
80. Stem cells for lung cancer?
    Cell, 121(6): 811-3. [Abstract] [Full-text]
81. Discrepancies and similarities in how patients with lung cancer and their professional and family caregivers assess symptom occurrence and symptom distress.
    J Pain Symptom Manage, 29(6): 572-83. [Abstract] [Full-text]
82. Emodin induces apoptosis in human lung adenocarcinoma cells through a reactive oxygen species-dependent mitochondrial signaling pathway.
    Biochem Pharmacol, 70(2): 229-41. [Abstract] [Full-text]
83. Expression of amino acid sequences of the chromogranin A molecule and synaptic vesicle protein 2 in neuroendocrine tumors of the lung.
    Virchows Arch, 446(6): 604-12. [Abstract] [Full-text]
84. P/Q-type calcium channel antibodies, Lambert-Eaton myasthenic syndrome and survival in small cell lung cancer.
    J Neuroimmunol, 164(1): 161-5. [Abstract] [Full-text]
85. Cytoplasmic expression of c-erbB2 in non-small cell lung cancers.
    Virchows Arch, 446(6): 596-603. [Abstract] [Full-text]
86. Advanced bronchioloalveolar carcinoma: a phase II trial of paclitaxel by 96-hour infusion (SWOG 9714): a Southwest Oncology Group study.
    Ann Oncol, 16(7): 1076-80. [Abstract] [Full-text]
87. Randomized phase III trial comparing cisplatin-etoposide to carboplatin-paclitaxel in advanced or metastatic non-small cell lung cancer.
    Ann Oncol, 16(7): 1069-75. [Abstract] [Full-text]
88. Epidermal growth factor receptor activating mutations in Spanish gefitinib-treated non-small-cell lung cancer patients.
    Ann Oncol, 16(7): 1081-6. [Abstract] [Full-text]
89. The transcriptional factor YY1 upregulates the novel invasion suppressor HLJ1 expression and inhibits cancer cell invasion.
    Oncogene, 24(25): 4081-93. [Abstract] [Full-text]
90. Pediatric inflammatory myofibroblastic tumor with late metastasis to the lung: case report and review of the literature.
    Pediatr Dev Pathol, 8(2): 224-9. [Abstract] [Full-text]
91. Optimization for the production of water-soluble polysaccharide from Pleurotus citrinopileatus in submerged culture and its antitumor effect.
    Appl Microbiol Biotechnol, 67(6): 759-66. [Abstract] [Full-text]
92. In vitro response of tumour cells to non-uniform irradiation.
    Phys Med Biol, 50(13): 3041-51. [Abstract] [Full-text]
93. Vinorelbine plus cisplatin vs. observation in resected non-small-cell lung cancer.
    N Engl J Med, 352(25): 2589-97. [Abstract] [Full-text]
94. Risk of lung cancer among white and black relatives of individuals with early-onset lung cancer.
    JAMA, 293(24): 3036-42. [Abstract] [Full-text]
95. Role of adjuvant chemotherapy in the treatment of non-small-cell lung cancer.
    Am J Health Syst Pharm, 62(13): 1365-9. [Abstract] [Full-text]
96. CXCR4 chemokine receptor and integrin signaling co-operate in mediating adhesion and chemoresistance in small cell lung cancer (SCLC) cells.
    Oncogene, 24(27): 4462-71. [Abstract] [Full-text]
97. Tobacco components stimulate Akt-dependent proliferation and NFkappaB-dependent survival in lung cancer cells.
    Carcinogenesis, 26(7): 1182-95. [Abstract] [Full-text]
98. Cytokines differentially regulate the synthesis of prostanoid and nitric oxide mediators in tumorigenic versus non-tumorigenic mouse lung epithelial cell lines.
    Carcinogenesis, 26(7): 1196-206. [Abstract] [Full-text]
99. Small cell neuroendocrine carcinoma of the breast: a report of three cases and review of the literature.
    J Clin Pathol, 58(7): 775-8. [Abstract] [Full-text]
100. Cell cycle related proteins as prognostic parameters in radically resected non-small cell lung cancer.
     J Clin Pathol, 58(7): 734-9. [Abstract] [Full-text]
101. Perceptions of lung cancer and smoking among college students in Jordan.
     J Transcult Nurs, 16(3): 245-54. [Abstract] [Full-text]
102. Genome-based identification of diagnostic molecular markers for human lung carcinomas by PLS-DA.
     Comput Biol Chem, 29(3): 183-95. [Abstract] [Full-text]
103. Characteristics of complement activation in mice bearing Lewis lung carcinomas treated by photodynamic therapy.
     Cancer Lett, 225(2): 215-23. [Abstract] [Full-text]
104. IL-20, an anti-angiogenic cytokine that inhibits COX-2 expression.
     Biochem Biophys Res Commun, 333(2): 470-5. [Abstract] [Full-text]
105. Infection of lung epithelial cells and induction of pulmonary adenocarcinoma is not the most common outcome of naturally occurring JSRV infection during the commercial lifespan of sheep.
     Virology, 338(1): 144-53. [Abstract] [Full-text]
106. Possible mechanism of metastasis in lung adenocarcinomas with a micropapillary pattern.
     Pathol Int, 55(7): 419-24. [Abstract] [Full-text]
107. Prognostic factors in surgically resected N2 non-small cell lung cancer: the importance of patterns of mediastinal lymph nodes metastases.
     Eur J Cardiothorac Surg, 28(1): 33-8. [Abstract] [Full-text]
108. Recurrent pulmonary mucinous cystadenoma.
     Eur J Cardiothorac Surg, 28(1): 176-7. [Abstract] [Full-text]
109. Detection of disseminated tumor cells in mediastinoscopic lymph node biopsies and lymphadenectomy specimens of patients with NSCLC by quantitative RT-PCR.
     Eur J Cardiothorac Surg, 28(1): 26-32. [Abstract] [Full-text]
110. Heterogeneous nuclear ribonucleoprotein B1 protein impairs DNA repair mediated through the inhibition of DNA-dependent protein kinase activity.
     Biochem Biophys Res Commun, 333(3): 888-95. [Abstract] [Full-text]
111. A long-term survival case of small cell lung cancer in an HIV-infected patient.
     Jpn J Clin Oncol, 35(6): 349-52. [Abstract] [Full-text]
112. Focal uptake of fluorodeoxyglucose by the thyroid in patients undergoing initial disease staging with combined PET/CT for non-small cell lung cancer.
     Radiology, 236(1): 271-5. [Abstract] [Full-text]
113. Automated detection of pulmonary nodules on CT images: effect of section thickness and reconstruction interval--initial results.
     Radiology, 236(1): 295-9. [Abstract] [Full-text]
114. Pulmonary nodules: automated detection on CT images with morphologic matching algorithm--preliminary results.
     Radiology, 236(1): 286-93. [Abstract] [Full-text]
115. Oxidized guanine lesions and hOgg1 activity in lung cancer.
     Oncogene, 24(28): 4496-508. [Abstract] [Full-text]

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